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B细胞的异常增殖在干燥综合征中的研究进展 被引量:2

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摘要 干燥综合征是一种主要累及外分泌腺的慢性炎症性自身免疫病,病理表现主要为T淋巴细胞和B淋巴细胞的大量浸润,产生大量的免疫球蛋白和自身抗体。近年B淋巴细胞在干燥综合征中的作用越来越被人重视,如:B细胞克隆性增殖,B淋巴细胞刺激因子诱导B细胞增殖和活化及以B细胞为靶向治疗干燥综合征等,这些研究让人们对干燥综合征的发病机制和治疗有了更深的认识。
出处 《安徽医药》 CAS 2009年第2期117-120,共4页 Anhui Medical and Pharmaceutical Journal
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参考文献23

  • 1David I Stott, Falk Hiepe, Michael Hummel, et al. Antigen-driven clonal proliferation of B cell within the target tissue of an autoimmune diease [ J ]. The American Society for Clinical Investigation Ine, 1998,102:938 - 6.
  • 2Salomonsson S, Jonsson MV, Skarstein K, Brokstad K, et al. Cellullar basis of ectopic germinal center formation and autoantibody production in the target organ of patients with Sjogren syndrome [ J ]. Arthritis Rheum ,2003,48 ( 11 ) :3187 - 1.
  • 3Prochorec-Sobieszek M, Wagner T, Loukas M, et al. Histopathological and immunohistochemical analysis of lymphoid follicles in labial salivary glands in primary and secondary sjogren syndrome[ J]. Med Sci Monit,2004,10(4) :115 -21.
  • 4Vojvodic D, Magic Z, Stefanovic D. Detection of B-lymphocyte clonality in samples of salivary gland tissue in patients with primary sjogren syndrome[ J]. Vojnosanit Preg1,2001,58 ( 5 ) :515 - 21.
  • 5Hansen A, Jacobi A, Pruss A, et al. Comparison of immunoglobulin heavy chain between peripheral and glandular B cells in a patient with primary sjogren syndrome [ J ]. S cand J Immunol, 2003,57 (5) :470 -9.
  • 6Tokuno T, Takahashi H, Suzuki C, et al. Analysis of B-cell clonality in the hepatic tissue of patients with sjogren' s syndrome[ J]. Scand J Rheumatol,2003,32(5 ) :268 - 72.
  • 7Daridon C, Pers JO, Devauchelle V, et al. Identification of transitional type IIB cells in the salivary glands of patients with sjogren syndrome[ J]. Arthritis Rheum ,2006,54 ( 7 ) :280 - 8.
  • 8Mariette X. Lymphomas in patients with sjogren syndrome :review of the literature and physiopathologie hypothesis [ J ]. Leuk Lymphoma, 1999,33:93 - 99.
  • 9Masaki Y, Sugai S. Lymphoproliferative disorders in Sjogren syndrome [ J ]. Autoimmun Rev,2004,3 (3): 175 - 82.
  • 10Vasil'ev VI, Probatova NA, Varlamova EIu, et al. Prognostic implications of mixed monoclonal cryoglobulinemia in Sjogren' s disease [ J ]. Tera Arkh, 2004,76 ( 8 ) : 61 - 8.

同被引文献20

  • 1王秦,刘爱武,付自力,刘秀梅.原发性干燥综合征心脏病变106例分析[J].临床医药实践,2005,14(8):573-574. 被引量:3
  • 2孙文闻,巩路.干燥综合征血清性激素水平与白细胞介素-6的相关性研究[J].中华风湿病学杂志,2006,10(1):36-39. 被引量:5
  • 3赵大爽.六味地黄丸治疗干燥综合征的疗效观察[J].光明中医,2006,21(4):50-51. 被引量:5
  • 4Van Woerkom JM,Kruize AA,Wenting MJG,et al.Salivary gland and peripheral blood T helper and 2 cell activity in Sjogrem Syndrome compared with non-Sjogrem Syndrome[J].Ann Rheum Dis,2005,64:1474-9.
  • 5Kohriyama K,Katayama Y. Disproportion of helper T cell subsets in peripheral blood of patients with primary Sj?gren's syndrome[J].Antoimmnnity,2000,(1):67-72.
  • 6Stockinger B,Bourgeois C,Kassiotis G. CD4+memory T cells:functional differentiation and homeostasis[J].{H}Immunological Reviews,2006,(1):39-48.
  • 7Wlladis EJ,KapilaR,Chu DS. Idiopathic CD4+lymphocytopenia and Sj?gren's syndrome[J].{H}Archives of Ophthalmology,2005,(7):1012.
  • 8Sumida T. Molecular mechanismin Sj?gren's syndrome T cell receptors and autoantigens[J].Rvumachi,2002,(5):769-776.
  • 9董怡.2002年修订的干燥综合征国际分类(诊断)标准[J]{H}中华风湿病学杂志,2002(4):257.
  • 10Watanabe N,GavrieliM,Sedy JR. BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1[J].{H}Nature Immunology,2003,(7):670-679.

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