顺铂腹腔热灌注并微波局部热疗对癌性腹水的疗效观察

Effects of intraperitoneal hyperthermal DDP perfusion and local microwave hyperthermotherapy on malignant ascites

目的观察顺铂腹腔热灌注联合微波局部热疗治疗癌性腹水的临床疗效及副反应。方法64例癌性腹水病人随机分为两组,治疗组32例采用顺铂腹腔热灌注并微波局部热疗;对照组32例单用顺铂腹腔热灌注治疗。结果治疗组有效率及KPS评分较对照组明显提高,两组比较差异有统计学意义。结论顺铂腹腔热灌注并微波热疗能显著提高癌性腹水的治疗效果,改善病人生存质量,值得临床推广应用。

Aim To observe the clinical effects and side-effects of the combined treatment of cisplatin （DDP） and the local thermotherapy with microwave for malignant ascites. Methods Sixty-four patients with malignant ascites were randomly divided into two groups. In the treatment group,32 patients underwent intraperitoneal hyperthermal DDP perfusion and local thermotherapy. The rest in the control group received intraperitoneal hyperthermal DDP perfusion only. Results The efficacy rate and KPS score in the treatment group were significantly higher than those in the control group. Conclusion The combination of intraperitoneal hyperthermal DDP perfusion and local thermotherapy improves the therapeutic effects for malignant ascites and patients＇quality of life,which is worth clinical application.