期刊文献+

大鼠神经干细胞体外培养及分化 被引量:1

下载PDF
导出
摘要 神经干细胞(neural stem ceils,NSCs)是一种能产生神经元和胶质细胞的前体细胞。它的发现是神经科学领域的重大进展,为神经发育研究与神经组织移植开辟了广阔的前景,在将来治疗诸如帕金森氏病等神经退行性疾病和神经损伤性疾病上有较为广泛的应用。源于人脑能不断增殖的神经干细胞对基础与临床神经科学尤其具有巨大的诱惑力,神经干细胞的长期分离培养与建系成为进一步中枢神经系统疾病治疗研究的首要任务。
出处 《浙江创伤外科》 2009年第1期21-23,共3页 Zhejiang Journal of Traumatic Surgery
基金 浙江省医药卫生科学研究基金资助项目(200402329)
  • 相关文献

参考文献7

  • 1Reynolds BA ,Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system [J]. Science, 1992,255 : 1701-1710.
  • 2Gritti A, Frolichsthal-Schoeller P, Galli R,et al. Epidermal and fibroblast growth factors behave as mitogenic regulators for a single multipotent stem cell-like population from the subventricular region of the adult mouse forebrain [J]. J Neurosci, 1999,19 : 3287-3297.
  • 3尹晓娟,巨容,封志纯.人胎脑神经干细胞的体外培养[J].中国微循环,2005,9(6):406-408. 被引量:1
  • 4Bez A,Corsini E,Curti D,et al.Neurosphere and neurosphereforming cells: morphological and ultrastructural characterization [J]. Brain Res, 2003, 993(1): 18-29.
  • 5向佳新,伍军,方方,陈风华,高俊伟,刘劲芳,王延金,邓永文.神经干细胞的分离培养及超微结构研究[J].中国现代医学杂志,2006,16(5):705-708. 被引量:3
  • 6Johansson CB, Momma S, Diana LC, et al. Identification of a neural stem cell in the adult mammalian central nervous system. [J]. Cell, 1999,96(1 ) :25-34.
  • 7Stefan A, Doris L, Klaus KB ,et al. Differentiation of green fluorescent protein-labeled embryonic stem cell-derived neural precursor cells into Thy-1-positive neurons and glia after transplantation into adult rat striatum [J]. J Neurosug,2000,93 (12):1026-1032

二级参考文献15

  • 1尹晓娟,封志纯,杜江.人胎脑皮质神经干细胞的分离培养及鉴定[J].中华检验医学杂志,2004,27(11):789-791. 被引量:9
  • 2沈雪莉,贾立红,石玉秀.神经干细胞向胆碱能神经元定向分化的探讨研究[J].中国现代医学杂志,2005,15(4):520-523. 被引量:11
  • 3Galza L,Fernandez M,Giuliani A,et al.Stem cells and nervous tissue repair:from invitro to in vivo[J].Prog Brain Res.2004,146(2):75-91.
  • 4Santa-Olalla J.Basic fibroblast growth factor promotes epidermal growth factor responsiveness and survival of mesencephalic neural precuror cells[J].J neurobiol.1999,40(1):14-27.
  • 5Galli R,Pagano SF,Gritti A,et al.Regulation of neuronal differentiation in human CNS stem cell progeny by leukemia inhibitory factor[J].Dev Neurosci.2000,22:86-95.
  • 6VESCOVI AL, PARATI AA, GRIT TI A, et al. Isolation and cloning of multipotential stem cell from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetie stimulation[J]. Exp Neurol, 1999, 156(1): 71-83.
  • 7STEFANO FP, FRANCESCO I, MARINA G, et al. Isolation and characterization of neural stem cells from the adult human olfactory bulb[J]. Stem Cells, 2000, 18: 295-300.
  • 8CARPENTER MK, XIA C, ZHONG YH, et al. I n vitro expansion of a multipotent pop ulition of human neural progenitor cells[J]. Exp Neurol, 1999, 158(2): 265-278.
  • 9MCKAY R, Stem cells in t he cent ral nervous system[J]. Science, 1997, 276(5309): 66-71.
  • 10LOBO MV, ALONSO FJ, REDONDO C, et al. Cellular characterization of epidermal growth factor-expanded free-floating neurospheres[J]. J Histochem Cytochem, 2003, 51: 89-103.

共引文献2

同被引文献7

引证文献1

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部