糖尿病心肌病50例临床特点分析

Clinical character analysis of diabetic cardiomyopathy

目的探讨糖尿病心肌病的临床特点。方法选择1997年7月—2007年6月在我院住院治疗的100例糖尿病患者,其中伴心肌损害50例,将患者分为两组作病例对照研究,糖尿病合并心肌病为病例组,未合并心肌病为对照组,比较两组一般特征、血脂代谢情况和心脏超声特点。结果两组性别、年龄比较差异无统计学意义(P>0.05),而病程比较差异有统计学意义(P<0.05),伴心肌损害的病例组病程明显长于对照组;两组总胆固醇(TC)值无差别,但甘油三酯(TG)、高密度脂蛋白(HDL)和低密度脂蛋白(LDL)差异有统计学意义(P<0.05),病例组患者甘油三酯高,但高密度脂蛋白和低密度脂蛋白较对照组低;糖尿病心肌病组患者左室舒张功能较对照组患者明显降低(P<0.05)。结论糖尿病病程长、甘油三脂高等因素是糖尿病心肌病发病的危险因素,治疗时强调对糖尿病患者进行宣传教育,有效控制高血糖、高血压及脂代谢紊乱对疾病的防治有重要意义。

Objective To explore the clinical character of diabetic cardiomyopathy. Methods Selected 100 diabetics, 50 of which with cardiac muscle damage, the patients were divided into ease group and control group, who with cardiac muscle damage are case group and that with no cardiac muscle damage are control group, we compared their common character, lipometablism and eordis ultrasonic. Results There were no statistical significance on the age and sex, but disease course, which of the case group was longer than the control group（ P 〈 0.05 ）, the difference of taral cholesterol（TC） in the two groups was not different, but triglyceride （ TG）, high density lipoprotein（HDL） and lower density lipoprotein（LDL） had statistical significance（ P 〈 0. 05 ）, TG of the case group was higher than the control group, while HDL and LDL were lower, the diastolic function of left ventricle in case group was lower than control group（ P 〈 0. 05 ）. Conclusion Long disease course, high TG and others are risk factors for diabetic eardiomyopathy, we should emphasize on educating and better controlling high blood sugar, high hypertension and lipid decompensation, it is useful to treat and prevent this disease.