不同刺激野的图形翻转视觉诱发电位

The PRVEPs Evoked by Different Fields Stimulation

目的研究正常人不同刺激野图形翻转视觉诱发电位(pattern reversal visual evoked potentials,PRVEPs)的特点及其法医学应用价值。方法对30名(60眼)正常视功能的受试者分别进行全屏刺激野、中心刺激野及周边刺激野刺激,记录并分析PRVEPs的潜伏期与波幅。结果正常人左、右眼之间PRVEPs各波潜伏期及波幅差异无统计学意义。除中心刺激野PRVEPs中N1波的出现率为36.77%外,各波在不同刺激野PRVEPs的出现率为100%。全屏刺激野与周边刺激野N1波潜伏期差异有统计学意义,波幅差异无统计学意义。P1波潜伏期及波幅在三种不同刺激野PRVEPs中差异均有统计学意义。结论应用不同刺激野的PRVEPs,可对视网膜不同区域的功能状态进行客观评定,并可以用于对受试者是否存在伪装或夸大视野缺损的评定。

Objective To study the character of the PRVEPs evoked by different stimulation fields in normal-vision subjects and its value in forensic medicine. Methods The PRVEPs were evoked by full-field, central-field and peripheral-field respectively in 30 subjects （60 eyes） and the latency and amplitude of N1 and P1 were analyzed. Results There was no statistically significant difference in the latency and amplitude of PRVEPs between right and left eyes. The appearance probability of all the waves was 100% at the different stimulations but that of N1 was 36.77% at the central-field. There was statistically significant difference in the latency of N1 at the full field and peripheral field stimulations and there was no statistically significant difference in the amplitude. There was statistically significant difference in the latency and amplitude of P1 at the full field, central field and peripheral field stimulation. Conclusion The PRVEPs evoked by different field stimulations can be used to evaluate the functions of the different area retina and can be used to identify the exaggerated or pretended visual dysfunction.