摘要
目的:HA-TCP/CS/骨碎补复合支架作为骨修复材料的可能性。方法:12只新西兰白兔随机分成两组,在下颌骨设计两处方形缺损,A组植入相应大小的骨碎补粉型复合材料,B组植入骨碎补溶剂型复合材料,分别于第2、4、8周末处死动物并取标本,行骨密度测定。结果:A组骨缺损区修复后骨组织骨密度测定结果显示新生骨质量较高,骨愈合情况优于其他组。结论:HA-TCP/CS/骨碎补复合材料应用于骨缺损修复可促进骨生成,且骨碎补粉型效果较好。
Objective： To study the possibility to use hydroxyaptite/triealcium- phosphosphate/chitosan （HA/TCP/CS）/rhizoma drynariae composite for bone defect repairing. Method： We divided 12 White rabbits into two groups：Group A and Group B and made two square bone defects on the submaxilla. The two defects was reconstructed with the powder form of composite in Group A and with the solvent form of composite in Group B, respectively. The reconstructive ability of bone defect was evaluated by bone densitometry. Results： The bone densitometry showed that the regeneration of new bone in Group A was better than that in Group B. Conclusion：The HA--TCP/CS / rhizoma drynariae can accelerate the osteogenesis and bone restoration. The powder form of rhizoma drynariae excelled the other forms.
出处
《黑龙江医药科学》
2009年第1期29-30,共2页
Heilongjiang Medicine and Pharmacy
