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PTEN基因与子宫内膜癌的研究现状 被引量:2

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作者 于洋 王兴华
出处 《黑龙江医药科学》 2009年第1期60-61,共2页 Heilongjiang Medicine and Pharmacy
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参考文献10

  • 1Li J, Yen C, Lian D, et al. PTEN, a putative protein tyrosinephosphatase gene mutated in human brain, breast, and prostate cancer[J]. Science. 1997,275( 12 ): 1943-1947
  • 2田新霞,吴浩强.新的肿瘤抑制基因PTEN[J].中华病理学杂志,2000,29(6):455-457. 被引量:14
  • 3周隽,吴强.肿瘤抑制基因PTEN的研究进展[J].癌变.畸变.突变,2002,14(2):131-134. 被引量:20
  • 4柯细松.PTEN抑癌机制的最新进展[J].国外医学(遗传学分册),2001,24(4):194-197. 被引量:13
  • 5Perren A, Weng LP. BoagAH, et al. Immunohistochemical evidence of loss of PTEN exp ression in primary ductal adenocarcinomas of the breast[J]. Am J Path.1999.155(4) :12532-12671
  • 6Tamura M ,Gu J,Matsumoto K.et al, Inhibition of cell migration,sp reading, and focal adhesions by tumor supp ressor PTEN[J]. Science, 1998,280(5369) : 1614-1617
  • 7Gu J, Tamura M. Yamada KM. Tumor suppressor PTEN inhibits integrin -and growth factor - mediated mitogen -activated protein (MAP) kinase signaling pathways[J]. J Cell Biol, 1998, 143 (5). 1375-1383
  • 8Salvesen HB. MacDonald N. Ryan A.et al, PTEN methylation is associated with advanced stage and microsatellite instability in en2dometriat carcinoma[J]. Int J Cancer,2001.91 (1) :22-26
  • 9Resinger J I. Hayes K, Maxwell GL,et al. PTEN mutation in endometrial cancers is associated with favorable clinical and pathologiccharacteristics[J]. Clin Cancer Res, 1998.4(12) :3005
  • 10Mutter GL.LinMC, Fitzgerald JT,et al. Altered PTEN ex2p ression as a diagnostic marker for the earliest endometrial p re2cancers [ J ]. J Natl Cancer Inst,2000,92(24):924-930

二级参考文献24

  • 1Tian X X,J Neuropathol Exp Neurol,1999年,58卷,472页
  • 2Furnari F B,Cancer Res,1998年,58卷,5002页
  • 3Gu J,J Cell Biol,1998年,143卷,1375页
  • 4Tamura M,Science,1998年,280卷,1614页
  • 5Li D M,Cancer Res,1997年,57卷,2124页
  • 6Li J,Science,1997年,275卷,1943页
  • 7Li J,Yen C,Liaw D,et al.PTEN,a putative protein tyrosine phosphatase gene mutated in human brain,breast and prostate cancer [J].Science,1997,275 (5308) :1 943~1 947.
  • 8Lee JO,Yang H,Georgescu MM,et al.Crystal structure of the PTEN tumor suppressor:implications for its phosphoinositide phosphatase activity and membrane association[J].Cell,1999,99(3):323~334.
  • 9Steck PA,Pershouse MA,Jasser SA,et al.Identification of a candidate tumor suppressor gene,MMAC1,at chromosome 10q23.3 that is mutated in multiple advanced cancers[J].Nat Genet,1997,15(4):356~362.
  • 10Stambolic V,Suzuki A,de la Pompa JL,et al.Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN[J].Cell,1998,95(1):29~39.

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二级引证文献5

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