摘要
辣椒素的化学组成主要为辣椒碱和二氢辣椒碱。辣椒碱具有镇痛、消炎、促进食欲、改善消化、抗菌、杀虫及对神经递质的选择性等药理作用。辣椒碱可以治愈和缓和一些难治愈慢性神经疼痛,可为这些疾病的治疗提供一条新的途径,是一个很有发展潜力的药物本文采用高效液相色谱法,通过对流动相、检测波长等分离条件的优化,建立了辣椒素的分析方法。经实验证实,本方法操作简单、重复性好、准确度高,可以对辣椒素的工业化生产提供帮助。方法回收率90%～92%,相对偏差:2.5%,相关系数:r=0.9956。
The chemical composition of Capsaicinoids is capsaicin and dihydrocapsaicin.Capsaicin has the effects of Analgesia,antiphlogosis,increasing the appetite,improving the digestion,antibacterial,disinfections and so on.Capsaicinoids can cure and mitigate some chronic neural ache,provide a new way for these disease treatments.Capsaicinoids is the medicine with high development potentials.In this paper,by the HPLC method and with the optimization of mobile phase and detection wavelength,the analysis method of Capsaicinoids was established.Experiments proved that the method has the characteristics of simple operation,good reproducibility, high accuracy and can provide help to the industrial production of Capsaicinoids.The Recovery rate,relative deviation and correlation coefficient of the method are 90%～92%,2.5% and 0.9956 respectively.
出处
《现代科学仪器》
2008年第6期67-69,共3页
Modern Scientific Instruments
