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胸水DNA异倍体及CEA测定对恶性胸腔积液的诊断价值 被引量:3

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摘要 目的探讨胸水DNA异倍体及癌胚抗原(CEA)在恶性胸腔积液诊断中的价值。方法对32例恶性胸腔积液患者和36例良性胸腔积液患者应用流式细胞术分析胸水DNA异倍体及放射免疫方法测定CEA,比较两组的测定结果。结果恶性胸腔积液患者中有21例DNA异倍体阳性,阳性率65.6%;良性胸腔积液组均为阴性。胸水CEA测定恶性组18例阳性,阳性率56.3%;良性组5例阳性,阳性率13.8%。两项指标良恶性组间比较差异都有统计学意义(P<0.01)。恶性胸腔积液组DNA异倍体与CEA同时阳性或其中一项阳性者29例,灵敏度为90.6%,特异度为100%。结论胸水DNA异倍体与胸水CEA联合检测对恶性胸腔积液诊断价值更大。
出处 《现代医学》 2008年第5期352-354,共3页 Modern Medical Journal
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