应用SF-36中文版对偏头痛患者生存质量的调查

Investigation of health-related quality of life in migraine patients with SF-36 Chinese Edition

目的探讨偏头痛患者生存质量的现状,分析其影响因素。方法采用健康状况量表SF-36中文版对122例偏头痛患者和112例健康者对照并进行现场问卷调查。用两样本t检验比较两组生存质量评分,以多元逐步回归分析筛选偏头痛组生存质量的影响因素。结果偏头痛组在生理功能、生理职能、躯体疼痛、总体健康、精力、社会功能、情感职能、精神健康等8个维度的评分上均显著低于对照组(P<0.01);偏头痛患者生理综合评分的影响因素有头痛频率、头痛程度、学历,心理综合评分的影响因素有头痛程度、头痛频率、病程、学历。结论偏头痛患者生存质量偏低,通过控制其影响因素,如头痛频率、程度等可能有助于改善患者的生存质量。

Objective To explore health-related quality of life and analyze associated factors in migraine patients. Methods SF-36 Chinese Edition was used to carry out the survey face-to-face in 122 migraine patients and 112 healthy controls. The scores of quality of life in the two groups were compared withTwo-Sample T-Test, and the influencing factors for the quality of life were screened in the migraine group with multiple stepwise regression analysis. Results Migraine group scored significantly lower than control group in all the 8 domains including physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. Factors associated with physical summary score were headache frequency, headache severity and education in migraine group; Factors associated with mental summary score were headache severity, headache frequency, duration of disease and education in migraine group. Conclusions Migraineurs had a reduced quality of life relative to healthy controls, quality of life for migraine suffers may be improved by intervening the associated factors, especially headache frequency and headache severity.