血尿酸水平与冠状动脉病变程度相关性分析

The correlation between serum uric acid level and coronary lesion severity

目的探讨血尿酸水平与冠脉病变程度的关系。方法选择98例冠状动脉造影患者,分为冠心病组80例,非冠心病组18例,冠心病组又分为单支病变组27例,双支病变组29例,多支病变组24例。常规检测血尿酸水平,分析各组血尿酸水平与冠状动脉病变程度的相关性。结果冠心病组血尿酸水平(339.45±88.04)μmmol/L,明显高于非冠心病组(293.92±74.51)μmmol/L(P<0.01),单支病变组(332.0±80.30)μmmol/L,双支病变组(337.81±95.72)μmmol/L,多支病变组(352.23±80.04)μmmol/L,血尿酸水平呈递增趋势。结论血尿酸水平与冠状动脉病变程度呈正相关。

Objective To investigate the correlation between serum uric acid level and coronary lesion severity. Methods The fasting venous blood samples were collected from 98 patients undergoing coronary angiogrphy （CAG）.80 being diag- nosed as with CHD and 18 without CHD. The CHD group was re-divided into three subgroups：single-branch ,double-branch and three-branch,analysed the correlation serum uric acid level and coronary lesion severity. Results The UA level of CHD （339.45±88.04）μmmol/L was significantly higher than that of the non-CHD group （293.92±74.51）μmmol/L （P〈0.01）.There was a trend of increase of UA level in the single-branch subgroup （332.0±80.30）μmmol/L,double-branch subgroup （337.81±95.72） μmmol/L, three-branch subgroup （352.23±80.04）μmmol/L. Conclusion The level of the UA is positively associated with the severity of coronary artery lesion.