口腔粘膜病损HPV的检测

Detection of human papillomavirus (HPV) in benign and malignant lesions of oral mucosa

应用PCR技术检测口腔粘膜病损中HPV的感染情况,病损包括白斑、扁平苔藓、慢性盘状红斑狼疮、日光性唇炎、鳞癌及鳞癌术后上皮高度增生共34例。结果表明在口腔癌与白斑中可存在HPV的感染,HPV可能是口腔癌的致病因子之一。

In this study, We examined the infection of HPV in oral mucosa lesions by PCR. The lesions included:13 leukoplakias, 12 Licken planus, 5 squamous cell carcinomas, 2 hyperplasias occuring after sec operated, 1 DLE and 1 actinic cheilitis. The result showed that HPV exists in some sec and leukoplakia. HPV may beone risk factor of oral Carcinogenes.