弓形虫感染对先天颅面畸形的影响

The influence of the toxoplasma infection on the congenital malformation of facial cranium

用酶联免疫吸附试验检测53例先天颅面畸形患儿弓形虫特异性抗体IgM和IgG,阳性率分别为9.43％和11.32％,对照组为2.70％,两组间有显著性差异;患儿母亲的职业、生活习惯及有无与猫密切接触史也有显著性差异(P<0.05)。提示先天颅面畸形病因中,弓形虫感染可能是重要因素之一。

In this study,53 cases with congenital malformation of facial cranium who were less than half-year old, had been detected the special toxoplasma antibodies IgM and IgG using Enzyme-Linked Immunosorbent Assay(ELISA)method, the positive rates were 9.43% and 11.32% , but the positive rate of normal children was 2.70 % . There was significant difference in the occupation, custom and the contact with cat of the mothers . This result has shown that toxoplasma infection may be one of the important factors which cause the congenital malformation of facial cranium.