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产超广谱β-内酰胺酶大肠埃希菌的基因型分布 被引量：2

Distribution of Genotypes in ESBLs-producing Escherichia coli
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摘要 目的了解产超广谱β-内酰胺酶(ESBLs)大肠埃希菌所产生的ESBLs的基因型特征。方法PCR通用引物扩增blaTEM、blaSHV、blaCTX-M和blaOXA基因后测序以确定其基因亚型。结果140株大肠埃希菌中68株产blaCTX-M-9,58株产blaTEM-1,35株产blaSHV,15株产blaCTX-M-1。结论产ESBLs的大肠埃希菌的主要流行型别为blaCTX-M-9型和blaTEM型。 Objective To determine the genotypes of ESBLs of Eseherichia coli （E.coli）. Methods Polymerase chain reaction （PCR） and DNA sequencing were used to determine ESBLs genotypes. Results 68 strains earried blaCTX-M-9 subgroup gene, 58 strains carried blaTEM-1 gene, 35 strains carried blaSHV subgroup gene, 15 strains carried blaCTX-M-1 subgroup gene. Conclusions blaCTX-M-9 group gene is prevalent as well as blaTEM group gene.
作者 张捍东 李旭
机构地区 安徽省宿松县人民医院感染病科 安徽医科大学第一附属医院感染病科
出处 《安徽医学》 2009年第2期171-173,共3页 Anhui Medical Journal
关键词 大肠埃希菌 超广谱Β-内酰胺酶 基因型 E. coli ESBLs Genotype
分类号 R450 [医药卫生—治疗学]
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参考文献10

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二级参考文献52

共引文献100

同被引文献24

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二级引证文献10

安徽医学
2009年 第2期

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