无创平板运动试验评分与冠状动脉造影预后指标的相关性

Correlation between noninvasive Duke treadmill score and prognostic marker of coronary angiography

目的探讨冠心病患者无创平板运动试验Duke评分(DTS)与冠状动脉造影评价预后的指标校正的TIMI帧数(CTFC)之间的相关性,为利用无创的平板运动试验评价冠心病患者的预后提供依据。方法对冠状动脉造影确诊为冠心病,并在造影前2周内完成平板运动试验的患者61例进行回顾性分析。根据DTS进行分组(≥5分为低危组、<5分为中高危组),分析DTS与CTFC的相关性,比较不同危险组间CTFC的差异。结果DTS与冠心病患者冠状动脉前降支(LAD)、回旋支(LCX)、右冠状动脉(RCA)的CTFC均呈负相关(r=-0·834、-0·769、-0·698,均P<0·01)。DTS低危组3支冠状动脉的CTFC值明显小于中高危组,组间CTFC值有明显差异[LAD:(21·3±1·7)帧vs(24·1±2·2)帧;LCX:(26·9±2·6)帧vs(30·6±3·4)帧;RCA:(21·1±4·0)帧vs(25·1±4·3)帧,均P<0·01]。结论冠心病患者平板运动试验Duke评分与LAD、LCX、RCA的CTFC值呈负相关。根据DTS得出的危险分层与CTFC有良好的相关性。

AIM To investigate the correlation between the non-invasive Duke treadmill score （DTS） and the corrected thrombolysis in myocardial infarction frame count （CTFC） in patients with coronary atherosclerotic heart disease. METHODS A total of 61 patients with coronary atherosclerotic heart disease, who underwent treadmill exercise tests at least 2 weeks before coronary angiography, were enrolled in our study. According to the value of DTS, we divided patients into ：2 groups： low-risk group （DTS≥5） and moderate-high-risk group （DTS 〈 5 ） , and the correlation between DTS and CTFC was evaluated. RESULTS DTS correlated negatively with CTFC of left anterior descending （LAD） , left circumflex artery （LCX） and right coronary artery （RCA） （r = - 0. 834, - 0. 769, - 0. 698, P 〈 0. 01 ）. CTFC in the low-risk group was much lower than that in the moderate-high-risk group [ LAD： （21.3 ±1.7 ） vs （24. 1 ±2.2）, LCX： （26.9±2.6） vs （30.6±3.4）, RCA：（21.1 ±4.0） vs （25. 1 ±4.3）, P〈0.01]. CONCLUSION There is a negative correlation between DTS and CTFC of LAD, LCX and RCA in patients with CAD. The risk stratification on the basis of DTS is notably associated with CTFC.