牛骨蛋白酶解制取肽钙的研究进展

Preparation of Polypeptide Calcium from Bovine Bone through Enzyme Hydrolysis

文章首先简要介绍了牛骨的成分,重点对羟基磷灰石和胶原蛋白的结构进行了描述;接着对常用酶的作用位点以及酶解的研究现状进行了详细介绍。通过对氨基酸螯合钙和多肽螯合钙的螯合和吸收机制进行比较,确定多肽螯合钙的优越性和研究的必要性,并对目前多肽螯合钙的结构分析方法,不同分子量多肽钙的分离以及多肽钙产品的研发情况进行了详细概括。

Composition of the bone was briefly introduced, and the structures of hydroxyapatite and collagen were particularly described in this paper. And then the enzyme active sites and enzyme hydrolysis were reviewed. Superiority and necessity of polypeptide chelate calcium （PCC） were found while the chelation and absorption mechanisms between amino acid chelate calcium （ACCC） and PCC were compared. Analysis methods of PCC structure, separation of polypeptide calcium （PC） with different molecular weight and the development of PC products were summarized in details.