摘要
目的了解大肠癌发生肝转移的临床相关因素。方法对63例发生肝转移及51例未发生转移的大肠癌患者的临床病理资料进行比较分析。结果病程(自出现症状至手术时间)超过半年肝转移率为67.3%,肿瘤低分化者肝转移率为80%,血清CEA、CA199值异常的患者发生肝转移率分别为100%和92.3%,与对照组(无肝转移组)比较,差异有统计学意义(P<0.05),且有淋巴结转移及肿瘤浸润较深者其肝转移率明显升高,差异亦有统计学意义(P<0.05)。结论大肠癌肝转移与患者病程、肿瘤浸润深度、分化程度、淋巴结转移、患者血清CEA、CA199值相关,应针对相关因素积极治疗,加强随访。
Objective To analyze clinical factors of hepatic metastases of colorectal cancer and to guide the individ- ualized and reasonable treatment. Methods 63 cases with hepatic metastases of colorectal cancer were retrospectively reviewed. Results Cases whose disease course over six months have a hepatic metastate rate 67.3 %. Cases with low differentiation have a hepatic metastate rate 80%. Cases with high expression level of CEA and CA199 have a hepatic metastate rate 100% and 92.3% respectively. Condusion For better proguosis,different measures should be taken in patients with different clinical factors.
出处
《宁夏医科大学学报》
2009年第1期58-61,共4页
Journal of Ningxia Medical University
关键词
大肠癌
肝转移
临床相关因素
colorectal cancer
hepatic metastases
clinical factors
