饮茶与女性肺癌关系的流行病学研究

TEA CONSUMPTION AND LUNG CANCER

调查研究饮茶与女性肺癌的关系。方法用全人群病例对照研究方法，调查６４９例３５～６９岁女性肺癌新病例，按频数配对随机配以６７５名对照。结果饮茶对非吸烟者肺癌有保护作用，ＯＲ＝０．６３，９５％置信区间＝０．４６～０．８７，ＯＲ值还随饮茶量增加而降低（趋势检验Ｐ＝０．００２７）。饮茶对各种组织类型的非吸烟者肺癌都有不同程度的保护作用。在吸烟者中，由于吸烟因素本身的干扰，未见饮茶的保护作用。结论饮茶对肺癌的保护作用值得进一步研究。

bjective:To investigate relationship between tea drinking and female lung cancer.Methods:649 new cases of female lung cancer aged 35 to 69 years with 675 population controls randomly sampled by use of frequency matching were involved in a population based casecontrol study.Results:Tea drinking showed protective effect against lung cancer among nonsmoking females, OR=063,95% CI=064～087,OR decreased with increase in the amount of tea consumed (trend test:P=00027) Tea drinking showed protective effect in different degree for all kinds of histological types of lung cancer among nonsmoking females. The protective effect was not seen among smokers due to interference of smoking itself as a strong risk factor.Conclusion:The protective effect of tea drinking warrants further investigation.