232例围手术期患者抗菌药物应用情况分析

Analization of antibacterials used in 232 perioperative patients

目的调查我院围手术期患者抗菌药物应用情况，评价用药合理性。方法回顾性分析我院232例围手术期患者抗菌药物应用情况。结果232例围手术期患者100％应用抗菌药物，品种选用以头孢菌素类为主占66％；Ⅰ类切口手术应用抗菌药物达100％，联合应用2种抗菌药物者78％；不今理用药占调查总数的45％，其中用法、剂量不合理者35％，用药时机不合理者13％，术后用药者59％，用药疗程过长者22％，药物选择不当者10％，作微生物培养及药敏试验者4％。结论我院围手术期抗菌药物的使用存在不合理之处，应加强规范化使用管理。

Objective To investigate antibacterials used in perioperative patients and evaluate the rationality of antibacterials. Methods Retrospectively analyze the antibacterials used in 232 perioperative patients. Results Antibacterials were used in all patients and cephalosporins were chosed in most patients, antibacterials were used in 66% patients with I kind incision and combination of two kind of antibacterials were used in 78% patients; antibacterials were used irrationally in 45% patients, usage or dose was irrational in 35% patients, medication juncture was unreasonable in 13% patients, antibacterials used after operation was 59%, time of therapy was too long in 22%, unreasonable drug were chosed in 10% patients, and microorganism culture and susceptibility test were done in only 4% patients. Conclusions antibacterials were used irrationally in periopertive patients in our hospital, and may strengthen the normalization of usage of antibacterials.