微量白蛋白尿:2型糖尿病慢性并发症的关键标志

Microalbuminuria:the key signs of chronic complications of type 2 diabetes.

微量白蛋白尿的出现是肾小球滤过膜损伤的结果,是糖尿病肾损害的最早临床征象;伴微量白蛋白尿的糖尿病患者其心血管病变的发生率及病死率明显增高。对糖尿病微量白蛋白尿期患者进行针对可能导致病情加重的多个危险因素的强化治疗,包括改变生活方式、严格控制血糖、RAS系统阻断、严格降压、他汀类调脂及抗凝等能延缓或阻止病变的进展。

microalbumin is the result of the glomerular filtration membrane injury and the first clinical sign of diabetic kidney damage. The cardiovascular disease incidence and mortality of diabetic with mieroalbuminuria is significantly increased. The intensive treatment of risk factors that may aggravate their condition, including life style changes, strict glycemic control, blocking the RAS, and strict control of the elevated blood pressure, lipid-lowering and anticoagulant treatment can delay or pre, cent the disease＇s progress.