摘要
对茚虫威关键中间体5-氯-2,3-二氢茚-1-酮的合成进行了研究。以3-氯苄基氯为原料,经亲核取代、水解、脱羧、酰氯化和付氏酰基化等5步反应生成目标产物,产率42%。
The main intermediate of 5-chloro-2,3-dihydro-lH-inden-1-one in the synthesis of indoxacarb was synthesized in this paper. The title compound was synthesized from 3-chlorobenzyl chloride, through nucleophilic reaction, hydrolyzation, decarboxylation, acyl chloride reaction and Friedel-Crafts acylation reaction in overall yield of 42%.
出处
《化学工业与工程》
CAS
2009年第2期147-149,共3页
Chemical Industry and Engineering
