期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

非离子通道阻滞剂的抗心律失常作用 被引量：3

原文传递
导出
摘要 传统的抗心律失常药主要依赖于阻断Na^＋、K^＋、Ca^2＋离子通道，包括I类、Ⅲ类和Ⅳ类抗心律失常药。由于多数治疗剂量的离子通道阻滞剂在患有器质性心脏病的患者中同时具有致心律失常的副作用，临床使用受到限制。近年来研究发现，心脏的机械牵张、炎症、氧化应激，心房肌细胞代谢，
作者 冉玉琴 浦介麟
机构地区 中国医学科学院北京协和医学院阜外心血管病医院心律失常诊治中心
出处 《中华心血管病杂志》 CAS CSCD 北大核心 2009年第2期186-188,共3页 Chinese Journal of Cardiology
关键词 离子通道阻滞剂 抗心律失常作用 Ca^2+离子通道 抗心律失常药 器质性心脏病 致心律失常 NA^+ 治疗剂量
分类号 R686 [医药卫生—骨科学]
  • 相关文献

参考文献27

  • 1Savelieva I, Camm J. Statins and polyunsaturated fatty acids for treatment of atrial fibrillation. Nat Cliu Pract Cardiovasc Med, 2008,5:30-41.
  • 2Bourque D, Daoust R, Huard V, et al. β-Blockers for the treatment of cardiac arrest from ventricular fibrillation? Resuscitation,2007,75 : 434444.
  • 3Bangalore S, Messerli FH, Kostis JB, et al. Cardiovascular protection using beta-blockers : a critical review of the evidence. J Am Coil Cardiol, 2007,50:563-572.
  • 4Dorian P. Antiarrhythmic action of beta-blockers: potential mechanisms. J Cardiovasc Pharmaeol Ther,2005,10 (Suppl) : 15- 22.
  • 5Imad AN, Anissa B, Jean-Se bastien H, et al. Prevention of atrial fibrillation onset by beta-blocker treatment in heart failure: a meta- analysis. European Heart Journal,2007, 28 : 457-462.
  • 6Haghjoo M, Saravi M, Hashemi MJ, et al. Optimal beta-blocker for prevention of atrial fibrillation after on-pump coronary artery bypass graft surgery: carvedilol versus metoprolol. Heart Rhythm, 2007, 4: 1170-1174.
  • 7Arshad A, Mandava A, Kamath G, et al. Sudden cardiac death and the role of medical therapy. Prog Cardiovasc Dis,2008, 50: 420-438.
  • 8Yin Y, Dalai D, Liu Z, et al. Prospective randomized study comparing amiodarone vs. amiodarone plus losartan vs. amiodarone plus perindopril for the prevention of atrial fibrillation recurrence in patients with lone paroxysmal atrial fibrillation. Eur Heart J ,2006,27 : 1841-1846.
  • 9Murray KT, Mace LC, Yang Z. Nonantiarrhythmic drug therapy for atrial fibrillation. Heart Rhythm,2007,4(Suppl) : S88-S90.
  • 10Jibrini MB, Molnar J, Arora RR. Prevention of atrial fibrillation by way of abrogation of the renin-artgiotensin system: a systematic review and meta-analysis. Am J Ther,2008 ,15 :36-43.

同被引文献12

  • 1陈灏珠,主编.实用心脏病学[M].第4版.443.
  • 2杨跃进,华伟,主编.阜外心血管内科手册[M].304.
  • 3陈灏珠,林果为.实用内科学[M].13版.北京:人民卫生出版社,2009:919.
  • 4Nomenclature and criteria for diagnosis of ischemic heart disease.Report of the Joint International Society and Federation of Cardiology/World Health Organization task force on standardization of clinical nomenclature[J].Circulation,1979,59(3):607-609.
  • 5Dernellis J,Panaretou M.Effect of C-reactive protein reduction on paroxysmal atrial fibrillation[J].Am Heart J,2005,150(5):1064.
  • 6Young-Xu Y,Jabbour S,Goldberg R,et al.Usefulness of statin drugs in protecting against atrial fibrillation in patients with coronary artery disease[J].Am J Cardiol,2003,92(12):1379-1383.
  • 7Kumagai K,Nakashima H,Saku K.The HMG-CoA reductase inhibitor atorvastatin prevents atrial fibrillation by inhibiting inflammation in a canine sterile pericarditis mode[J].Cadiovasc Res,2004,62(1):105-111.
  • 8Shiroshita-Takeshita A,Schram G,Lavoie J,et al.Effect of simvastatin and antioxidant vitamins on atrial fibrillation promotion by atrial-tachycardia remodeling in dogs[J].Circulation,2004,110(16):2313-2319.
  • 9Siu CW,Lau CP,Tse HF.Prevention of atrial fibrillation recurrence by statin therapy in patients with lone atrial fibrillation after successful cardioversion[J].Am J Cardiol,2003,92(11):1343-1345.
  • 10浦介麟,李宁.心律失常发生机制与治疗——参松养心胶囊心电生理学研究[N].中国医学论坛报,2007-01-25(A10).

引证文献3

二级引证文献3

中华心血管病杂志
2009年 第2期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部