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诱导型siRNA技术及其应用研究进展 被引量:1

The research progress of inducible siRNA technology and application
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摘要 RNA干扰为基因和蛋白质学的研究等提供了崭新的技术方法,诱导型siRNA主要是通过构建诱导型siRNA表达载体,实现siRNA技术对目的基因的可调控表达,为基因功能的研究、疾病基因治疗、疾病模型的建立、药物筛选等提供更完善的研究方法。本文主要对诱导型siRNA近年来的发展和应用进行综述。 RNA interference supply a new technology and method. By constructing inducible siRNA expression vector, inducible siRNA can regulate objective gene expression. Inducible RNAi will offer a method for gene function study, disease gene therapeutic,the construction of disease model, drug screening and so on.
出处 《中国病原生物学杂志》 CSCD 2009年第1期56-58,75,共4页 Journal of Pathogen Biology
基金 山东省自然科学基金项目(No.Y2007C152)
关键词 诱导RNAi技术 应用 综述 Inducible RNAi technology application review
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