癫痫的脑电图与神经影像

Study of EEG and neurological imaging in epilepsy

对７９例癫痫患者的脑电图与神经影像学对比研究，其中４０例进行外科治疗，部分病人手术标本送病理。结果发现：①顽固性癫痫患者脑结构及脑功能异常率均较高，分别为６２％和９６％。②全身性癫痫患者影像学异常率较低为１８％；部分性癫痫患者影像学异常率较高达６９％。③部分性癫痫患者影像学与电生理放电部位一致者６０％，不一致者４０％，不一致多为脑结构弥散性异常。④影像学阴性的病人病理显示胶质细胞增生。结果提示顽固性癫痫病人大多为脑结构异常所致，影像学可以显示较大的病变，但未能显示致痫灶的变化，如胶质细胞增生，神经细胞缺失等。

EEG and neurological imaging in 79 epilepsy were compared,40 of them were operated.Some operative sample were examined by pathological test.The result was as follows:①The abnormal rate of brain neuroradiological imaging in generalized seizure was lower than in partial seizure,they were 18% and 69% respectively.②The EEG localization was congruent with the side of the lesion in 60% for partial epilepsy. The noncongruent was 40%,most of them have widespread abnormal brain structure on radiological imaging. The pathological manifestation of cortical section showed neurons pyknosis and gliocyte hyperplasia, the pathological changes were seizure focus caused seizure. Neuroradiological imaging could show leision but not find seizure focus.EEG may demonstrate the electrical activity of epileptiform focus