超声诊断胎儿18-三体综合征

UItrasonography in fetuses with trisomy 18 syndrome

目的探讨产前常规超声检查对18-三体综合征胎儿的l临床诊断价值。方法对11例18-三体综合征胎儿常规超声声像图进行回顾性分析。结果18-三体综合征胎儿常表现为多发性严重畸形。胎儿生长受限(FGR)、脉络丛囊肿、心脏畸形较为常见;握拳手指交搭、摇椅状足底、草莓头颅是其特征性表现。结论超声诊断胎儿18-三体综合征安全、可靠、快捷、实用。

Objective To assess the value of ultrasonography in the prenatal diagnosis of trisomy 18 syndrome.Methods Ultrasonic manifestations of 11 fetuses with trisomy 18 syndrome were retrospectively analyzed.Results Multiple abnormalities,including fetal growth restriction（FGR）,choroid plexus cysts and heart abnormalities were the manifestations of prenatal ultrasonography of trisomy 18 syndrome.Abnormal hand posturing（overlapping flexed fingers）,rocker-bottom feet and abnormal head shape（strawberry sign）were characteristic findings.Conclusion Ultrasonography is a safe and practical method with great value in the diagnosis of fetal trisomy 18 syndrome.