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左布比卡因用于硬膜外麻醉60例分析 被引量:3

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摘要 目的观察0.33%左布比卡因在硬膜外麻醉下接受下腹部或下肢手术中的应用效果,并与0.5%左布比卡因比较。方法选择ASAⅠ或Ⅱ级连续硬膜外下接受下腹部或下肢手术的患者60例,随机分为2组,每组30例。试验组为以2%利多卡因诱导,再辅以约0.33%左布比卡因(即2%利多卡因5 ml加0.5%盐酸左布比卡因10 ml混合液)。对照组则直接以0.5%左布比卡因诱导麻醉。药物有效性通过感觉阻滞起效时间,运动阻滞起效时间,运动阻滞程度与腹肌松弛度等指标评定。结果加有2%利多卡因的左布比卡因比0.5%左布比卡因的感觉阻滞起效时间与运动阻滞起效时间要短,且腹肌松弛度优秀率要高。结论0.33%左布比卡因可为硬膜外下行下腹部或下肢手术提供良好的麻醉效果,且起效时间快,腹肌松弛度好,药物浓度低,安全性更高。
出处 《福建医药杂志》 CAS 2009年第1期43-44,共2页 Fujian Medical Journal
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