住院精神分裂症患者代谢综合征的患病率及相关因素

Prevalence of metabolic syndrome and its related factors in schizophrenic inpatients

目的了解住院精神分裂症患者代谢综合征的患病率及其相关因素。方法对上海市精神卫生中心分部住院的精神分裂症患者作调查,测定其代谢指标,采用世界糖尿病联盟(IDF)全球统一标准定义代谢综合征。结果共入组483人,其中男性272人(56.3%),女性211人(43.7%),平均年龄(53±10)岁(19～82岁)。住院精神分裂症患者代谢综合征的患病率为43.9%(213/483),女性的患病率(118/211,55.9%)高于男性的(94/272,36.4%)(χ2=22.0,P<0.05)。患病率随年龄增加而增加。大于41岁的患者中女性的代谢综合征患病率均高于男性。Logistic回归发现代谢综合征与性别有关。结论在精神分裂症患者尤其女性患者中存在较多的代谢综合征,疾病早期即应予以关注。

Objective： To investigate the prevalence of metabolic syndrome in schizophrenic inpatients and its relative factors. Methods ： Four hundred and eighty - three schizophrenic inpatients treated in Shanghai Mental Health Center Branch were investigated. Metabolic indexes were measured. The criteria of metabolic syndrome was based on the consensus definition released by the International Diabetes Federation. Results：Two hundred and seventy - two male and 211 female patients [ mean age （53 ± 10） years] were involved. The prevalence of metabolic syndrome was 43.9% , increased with the age. It was higher in female than that in male patients （55.9% vs 36.4% , P 〈 0.05 ）. After stratified by age, the prevalence was still higher in female whose age was above 41. Metabolic syndrome was related with sex in Logistic regression analysis （ P 〈 0.05 ）. Conclusion： Metabolic syndrome occurres in many schizophrenic inpatients, especially in female patients. Much attention should be paid even in the early course of illness.