摘要
以氰胺和异丙醇制备异丙氧基脒甲烷磺酸盐,再与三氟乙酰乙酸乙酯反应制得2-异丙氧基-4-羟基-6-三氟甲基嘧啶,最后与(E)-2-[2-(氯甲基)苯基]-3-甲氧基丙烯酸甲酯反应合成目标产物嘧螨酯,其结构经核磁、红外验证。生物活性测定结果表明该化合物具有良好的杀螨活性。
Fluacrypyrim was synthesized by reacting （E）-methyl 2-（2-（chtoromethyl）phenyl）-3-methoxyacrylate with 2-isopropoxy-6-（trifluoromethyl）pyrimidin-4-ol prepared from ethyl 4,4,4-trifluoro-3-oxobutanoate and isopropyl carbamimidate methanesulfonate prepared from cyanamide and propan-2-ol, and its structure was confirmed by 1H NMR and IR. The biological test results show that fluacrypyrim has good acaricidal activity.
出处
《农药》
CAS
北大核心
2009年第3期169-171,共3页
Agrochemicals
关键词
嘧螨酯
合成
杀螨活性
fluacrypyrim
synthesis
acaricidal activity
