膀胱癌患者行膀胱灌注应用盐酸利多卡因凝胶留置尿管的效果观察

The effects of lidocaine hydrochloride gel on the catheterization with bladder irrigation chemotherapy

目的观察老年膀胱癌患者在膀胱灌注中应用盐酸利多卡因凝胶留置尿管的效果。方法将50例需灌注化疗前置管的老年膀胱癌患者随机分为两组,实验组在置管前先用10ml盐酸利多卡因凝胶经尿道表面麻醉,然后按常规方法将尿管置入;对照组按常规方法应用液体石蜡油润滑后留置尿管。采用Zung氏焦虑自评量表(SAS)观察患者灌注前和灌注后的主观感受。结果实验组留置尿管后焦虑反应(SAS44.49±5.24分)低于对照组(52.95±9.16分),实验组留置尿管一次成功率(100%)明显高于对照组(88%),差异均有统计学意义(P<0.01)。结论盐酸利多卡因凝胶可明显减轻老年膀胱癌患者行膀胱灌注时留置尿管的焦虑反应,提高置管的一次成功率。

Objective To observe effects of lidocaine hydrochloride gel on catheterization in old patients with bladder irrigation chemotherapy. Methods 50 old patients with bladder cancer who needed to place urinary catheter for irrigation of bladder were randomly divided into two groups. The patients in experimental group were infused 10 ml lidocaine hydroehloride gel into urethra for mucosa surface anesthesia before insertting catheter,and then catheter was placed by conventional methods. The patients in control group were placed urinary catheter after using liquid lubrication oil. The score of Zung＂ s anxiety by selfrating seale（SAS）was used to subjective reaction before and after bladder irrigation. Results There was no significant difference of the score of anxiety reactions between before and after irrigation in the experimental group.However, an apparent anxiety reaction could be observed in the control group after irrigation. The one-time success rate of placing catheter in the experimental group reached 100% but 88% in the control group. The difference of the success rate between two groups was significant （P〈0.01）. Conclusions Lidocaine hydrochloride gel could significantly reduce the anxiety reaction of catheterization in old patients and increase the one-time success rate of catheterization.