缺血性脑血管病认知推理障碍的研究

Study on the inferential impairment caused by ischemic cerebrovascular diseases

目的探讨缺血性脑血管病患者认知推理能力损害情况,为血管性认知障碍的早期诊断要点提供线索。方法利用神经心理学检查方法对75例缺血性脑血管病患者和30例健康对照者进行简明精神智能量表(MMSE)、瑞文标准推理测验联合型(CRT)检查。结果缺血性脑血管病组的MMSE总分和CRT检查得分明显差于健康对照组(P<0.01)。75例缺血性脑血管病组出现推理障碍者54例(72%)。MMSE得分高者对应的瑞文推理测验IQ得分也高,相关分析呈正相关(r=0.647,P<0.01)。结论缺血性脑血管病后出现推理障碍相当普遍,不容忽视。

Objective To discuss the damage of cognitive inferential ability of ischemic cerebrovascular disease in order to provide clues for the highlight of early diagnosis of vascular cognitive impairment （VCI）. Methods Seventy-five cases of ischemic eerebrovascular disease patients and 30 controls were investigated. All the cases were detected by neuropsychological tests with mini mental state examination （MMSE） and combined Raven＇s test （CRT）. Results The isehemic cerebrovascular disease subjects performed significantly low in the total score of MMSE and intelligence quotient （IQ） of the test CRT compared with those in controls（P〈0.01）. According to the score of CRT-IQ, the incidence of inferential impairment was 72% in ICVD group. There was obvious relativity between the low scores of MMSE in ICVD patients and the low scores of and CRT-IQ（r =0. 647, P〈0. 01）. Conclusion The inferential impairment frequently oecuring in patients with ICVD can not be ignored.