40例精神分裂症伴糖尿病患者生活质量的对照研究

A compared study on quality of life for schizophrenics with diabetes

目的：探讨精神分裂症伴糖尿病患者的生活质量及影响因素。方法：采用MOS健康状况调查问卷（SF-36）、简明精神病评定量表（BPRS）等对40例精神分裂症伴糖尿病患者进行评定，并与40例精神分裂症患者资料进行对照比较。结果：分裂症糖尿病组患者SF-36总评分及其角色生理、生理机能、社会功能和角色心理状况等因子分均明显低于分裂症对照组，其间差异有显著性（P〈0．05），而两组间在躯体疼痛、主观健康状况、活力和心理健康状况等方面的评分差异无显著性（P〉0．05）。分裂症糖尿病组患者BPRS的活力缺乏因子分明显高于分裂症对照组，差异有非常显著性（P〈0．01），而BPRS总分及其它因子分两组间差异无显著性（P〉0．05）。不同的糖尿病诊断分型、病程和是否伴有合并症、严重并发症的精神分裂症患者的SF-36总分间差异有显著性（P〈0．01或P〈0．05）。不同的分裂症分型、病程、药物剂量、种类的SF-36总分间差异亦有显著性（P〈0．05）。结论：伴糖尿病的精神分裂症患者的生活质量较单纯的精神分裂症患者更差，医院、社会和家庭应对这部分患者的治疗、护理给予更多的支持。

Objective：To investigate the quality of life and influential factors for schizophrenics with diabetes. Methods：40 schizophrenics with diabetes were enrolled in the study group and 40 patients with schizophrenia were conducted in the control group. SF -36 and BPRS were used to evaluate the quality of life for both of the two groups. Results： The total score of SF -36 and the factor scores of role - physical （ RP）, physical functioning （ PF）, social functioning （SF） and role - emotional （ RE ） in the study group were much lower than those in the control group. So there were significant differences between the two groups （ P 〈 0. 05 ）. However, there were few differences in scores of bodily pain （BP）, general health （GH）, vitality （V）and mental health（MH） between both groups （P 〉 0.05）. The factor score of ANEG of BPRS in the study group was much higher than that in the control group. So there were great differences between them （P 〈 0. 01 ）, whereas there were no remarkable differences in the total score of BPRS and the other factor scores （P 〉 0.05 ）. The differences among the total scores of SF - 36for schizophrenics with different kinds of diagnosis for diabetes, the course and whether complications were accompanied or not were of great significance （P 〈 0.01 or P 〈 0.05）. So it was with schizophrenics of different types, course, dosage （P 〈 0.05 ）. Conclusions： The quality of life of schizophrenics with diabetes is worse than that of schizo- phrenics. Hence, more attention should be paid to these patients for their treatment and nursing.