认知治疗对50例精神分裂症患者服药依从性影响的研究

of cognitive therapy on the drug compliance in patients with Schizophrenia

目的：探讨认知治疗对精神分裂症患者服药依从性的影响。方法：将100例精神分裂症患者随机分为干预组和对照组，均接受系统的抗精神病药物治疗，干预组在此基础上进行认知治疗，而对照组仅限于一般健康教育。随访观察18个月。结果：两组患者服药依从性与生活质量均以干预组较好，且差异有显著性。不良行为发生人次、复发人数均以干预组较对照组少，差异有显著性。BPRS及PANSS评定结果均以干预组较对照组分值低，差异有显著性。结论：认知治疗能有效提高精神分裂症患者服药依从性，减少患者不良行为发生，提高患者生活质量，降低复发率。

Objective ： To explore the affect of cognitive therapy on the drug compliance of schizophrenic patients. Methods ：50 schizophrenic patients have been intervened with the cognitive therapy during they have the medicine for 18 months, and then compared 50 patients with receiving no special cognitive therapy. Results ： All the indexes which had obtained after the cognitive therapy were significant better than those with no cognitive therapy. Conclusions ： The cognitive therapy can effectively reinforce the compliance of the schizophrenic patients, and then improve the quality of life for them.