摘要
应用原位末端标记法（ＴＵＮＥＬ）及免疫组化技术对３２例胃低分化腺癌石蜡包埋组织切片进行检测，结果发现，胃癌组织中有细胞凋亡和ＢｃＬ－２蛋白的表达，二者阳性率分别为８１．２５％和６８．７５％，ＢｃＬ－２表达越明显的区域，细胞凋亡越少。实验结果提示，ＢｃＬ－２蛋白可能通过抑制细胞凋亡而参与胃癌的发生与发展。
In the experiment,the apoptosis and BcL2 expression were found in 32 samples of gastric cancer by TUNEL and immunohistochemical method.The positive rates were 81.25%(26/32) and 68.75%(22/32),respectively,and negative correlation was showed.The results indicated that BcL2 expression may participate in occurrence and development of gastric cancer by inhibition of apoptosis.
出处
《哈尔滨医科大学学报》
CAS
1998年第1期6-7,共2页
Journal of Harbin Medical University
基金
省科委八五攻关课题
