摘要
采用激光衍射法检测30例脑梗塞病人和30例同年龄正常人的红细胞变形指数(DI),发现在200dyn/cm2剪切力下,病人组DI值较正常对照组明显降低;同时还测定了两组红细胞膜脂质成分—膜胆固醇(Ch)、磷脂(Pl),二者比值(Ch/Pl)及血浆脂质等成分。结果膜Ch、Ch/Pl明显高于后者,血浆HDL-C、ApoA-I明显降低,ApoB明显升高,而血总胆固醇(TC)无升高。相关分析发现,DI值与Ch/Pl呈负相关。膜Ch与HDL-C、ApoA-I呈负相关,与ApoB呈高度正相关。
With laser diffractometers,the erythrocyte deformability (ED) was tested for 30 patients with cerebral infarction and 30 normal subjects.The data showed that ED index (DI) in patients was significantly lower than that in controls,under the shear stress of 200dyn/cm2.Erythrocyte membrane cholesterol (Ch),phospholipids (Pl) and serum lipid were also determined and analysed in the two groups.The results showed that total cholesterol (TC) was not higher,but ApoB was significantly higher,while ApoAI,HDLC in patients were significantly lower than that in the control group.We also found that ED was negatively associated with membrane Ch/Pl,positively with the ApoAI,however,the amount of membrane Ch was positively with ApoB,but had no association with TC.
出处
《哈尔滨医科大学学报》
CAS
1998年第2期119-121,共3页
Journal of Harbin Medical University
关键词
动脉硬化
脑梗塞
红细胞变形
膜脂质血浆脂类
Arteriosclerosis
Cerebral infarction
Erythrocyte deformability
Erythrocyte membrane lipid
Serum lipid