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危重病人并多系统功能衰竭伍用大剂量维生素C治疗的探讨

Observation on the Use of Large Dose of Vitamine C in Critical Patients Accompanied by Multiple Systems Organ Failure
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摘要 对38例危重病人并发多系统器官功能衰竭(MOSF)进行了回顾分析,并探讨了伍用大剂量维生素C(VC)治疗的可能性。本组病人MOSF的发生器官以肾、肝、心和外周循环发生率最高,其次为肺及消化、神经和凝血系统。VC治疗组20例MOSF死亡9例(45%),对照组18例死亡12例(66.7%)。两组比较前者死亡率低于对照组(P≤0.05)。本文结果表明,在综合治疗MOSF的基础上应用大剂量VC具有一定价值。 38 of critical patients accompanied by multiple systems organ failure (MOSF) and the probable treatment of large dose of vitamine C were analysed in the paper.We revealed that the organ occurrence of MOSF was,in turn,kidney,liver,heart,peripleral circulatory system(shock),lung and digestive,nervous,metabolic and blood coagulation system.The large dose of vitamine C was used in 20 patients with MOSF.9 of them died in this group (45.0%).In control group,12 of 18 patients died (66.7%).For comparison,the death rate was less in the patients used vitamine C than in the control patients (P≤0.05).The results showed that the use of large dose of vitamine C was clinically feasible on the basis of combined treatment of MOSF.
出处 《哈尔滨医科大学学报》 CAS 1998年第2期122-124,共3页 Journal of Harbin Medical University
关键词 维生素C 多器官衰竭 剂量 危重病 Multiple systems organ failure Vitamine C Stress
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