急性心肌梗死患者血脂及高敏C反应蛋白水平变化分析

Variation of Blood Lipids and High Sensitivity C-reactive Protein in Patients with Acute Myocardial Infarction

目的:探讨急性心肌梗死(AMI)患者的血脂及高敏C反应蛋白(hs-CRP)水平变化及临床意义。方法:测定86例AMI患者和90例稳定型冠心病(SCHD)患者的血脂及hs-CRP水平并进行对比分析。结果:总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)AMI组低于SCHD组;高敏C反应蛋白(hs-CRP)AMI组高于SCHD组;AMI组hs-CRP与TC、LDL-C呈负相关(r分别为-0.389和-0.412,P<0.01)。结论:AMI早期动态检测患者血脂和hs-CRP水平有助于及时掌握冠心病的严重程度和变化状况。

Objective： To explore variability of blood lipids , high -sensitivity C -reactive protein （hs - CRP） and clinical significance in acute myocardial infarction （ AMI ） patients. Method： The level of the blood lipids and hs - CRP of 86 patients with AMI and 90 patients with stable coronary heart disease （SCHD） were tested and comparably analyzed. Result： The TC , TG, LDL - C of patients with AMI were much lower than those of patients with SCHD ;The hs - CRP of patients with AMI was much higher than that of patients with SCHD;The concentration of hs- CRP was negatively related with serum levels of TC , LDL -C （r = - 0.389 , - 0.412 , respectively , P〈0. 01） in patients with AMI. Conclusion：The blood lipids and hs - CRP level is closely related to AMI and can be regarded as an indicator of severity and variation for CHD.