超声造影在HIFU治疗肝癌近期疗效评价中的应用

Application of contrast-enhanced ultrasound in evaluating short-term effect of liver cancer treated by HIFU

目的探讨超声造影在评价HIFU治疗肝癌近期疗效中的价值。方法利用三维超声造影和增强CT观察26例原发性肝癌的29个肿瘤病灶的影像学变化。结果高强度聚焦超声(HIFU)治疗前超声造影和增强CT检查,病灶表现为快进快出典型灌注模式者为27/29(93.1%)个和26/29(89.7%)个,二者比较差异无统计学意义(P>0.05);HIFU后超声造影和增强CT检查25/29个病灶(86.2%)表现为边界清楚的肿瘤灌注缺损,且可见边缘锐利光滑的环状增强带。结论超声造影和增强CT均可较准确地评价HIFU治疗肝癌的疗效,二者比较差异无统计学意义。超声造影是评价HIFU治疗肝癌后近期疗效的重要方法之一。

Objective To investigate the value of contrast - enhanced ultrasound （CEUS） in evaluating the short - term effect of liver cancer treated by HWU. Methods Twenty- nine tumors of 26 patients with primary liver cancer were observed by CEUS and enhanced - CT. Results Before HIFU treatment, there were 27 cases （27/29, 93.1% ） and 26 cases （26/29,89.7 % ） diagnosed by CEUS and enhanced CT respectively, and their appearance was ＂fast - in and fast - out＂ typical perfusion. There was no significant difference between the two group. 25 of 29 tumors were found by CEUS and enhanced CT after HIFU treatment, their appearance was sharply defined tumor perfusion defect, and the edge of ring enhancement zone was sharp and smooth. Conclusion CEUS and enhanced - CT beth can accurately evaluate the effect of liver cancer treated by HIFU, there is no significant difference between two methods. While CEUS is one of the important methods to evaluate the short - term effect of liver cancer treated by HIFU.