期刊文献+

经皮冠状动脉介入术后支架内血栓对临床预后的影响 被引量:5

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摘要 目的评价经皮冠状动脉介入(PCI)治疗后支架内血栓形成的危险因素及其对临床预后的影响。方法入选我院资料库登记成功实施PCI治疗的1283例患者。男860例,女423例,年龄(61.2±8.3)岁(14~84岁)。围手术期采用阿司匹林、氯吡格雷/噻氯匹定、低分子肝素/普通肝素进行标准的三联抗血小板、抗凝治疗。PCI手术方案:经股(桡)动脉入路,按标准的PCI手术规范治疗。平均随访(12±8)月(4-23月)。结果在1283例常规PCI患者中发生12例次支架内血栓形成,发生率为0.94%(12/1020)。其中急性支架内血栓1例,亚急性血栓9例,延迟血栓2例。合并危险因素,急性冠脉综合症(ACS)10例,弥漫长病变8例,心功能不全8例。临床转归:8例治愈出院,死亡4例。死亡的4例均为心绞痛并LAD支架内血栓形成,3例合并严重心功能不全。结论支架内亚急性血栓多发生于ACS、弥漫长病变、支架贴壁不良及心功能不全患者。合并不稳定性心绞痛、心功能不全、前降支支架内血栓形成是导致患者死亡的主要原因之一。
出处 《南方医科大学学报》 CAS CSCD 北大核心 2009年第1期165-166,169,共3页 Journal of Southern Medical University
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参考文献10

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