2005～2007年广州地区住院肺炎患儿腺病毒感染分析

Adenovirus infection in hospitalized children with pneumonia in Guangzhou from 2005 to 2007

目的了解广州地区住院肺炎患儿腺病毒感染情况。方法对2005～2007年广州地区腺病毒感染住院肺炎患儿的感染率、住院时间与费用等进行分析。结果腺病毒感染率6.04%,男女感染比1.47∶1,男女感染率(分别为5.21%和7.92%)有统计学差异(P<0.05),男女住院时间及费用无统计学差异(均P>0.05)。0～6岁患儿占总感染患儿数的90.50%,0～1岁感染率(3.71%)显著低于其他各年龄段感染率(P<0.05)。虽然冬季感染率(8.44%)显著高于春、夏、秋各季感染率(均P<0.05),但春夏季(3～8月)感染患儿数占总感染患儿数的60.11%。2007年感染率(4.31%)显著低于2005年(7.11%)、2006年(6.71%)感染率(均P<0.05)。结论腺病毒是广州地区住院肺炎患儿的重要病原,且在不同性别、年龄、季节和年度间感染存在差异。

Objective To understand the characteristics of adenovirus infection in hospitalized children with pneumonia in Guangzhou area. Methods The infection rate, hospitalization time and hospitalization expenses of adenovirus-infected hospitalized children with pneumonia in Guangzhou area from 2005 to 2007 were analyzed. Results The total adenovirus infection rate was 6.04% in these children, with a male to female ratio of 1.47：1, showing significantly higher infection rate in female （7.92%） than in male patients （5.21%, P〈0.05）. The hospital stay and hospitalization costs between male and female children showed no significant difference （P〉0.05）. Adenovirus-infected children fi＇om birth to six years old accounted for 90.50% of the total adenovirus-infected children, and the infection rate in 0 to 1-year-old children （3.71%） was significantly lower than that in elder children （P〈0.05）. Although the infection rate in winter （8.44%） was significantly higher than that in the other seasons （P〈0.05）, the cases from March to August accounted for 60.11% of the total infected cases. Furthermore, the infection rate in 2007 （4.31%） was significantly lower than that in 2005 and 2006 （7.11% and 6.71%, respectively, P〈0.05）. Conclusion Adenovirus infection is an important pathogen in hospitalized children with pneumonia in Guangzhou area, and the infection rates differed between gender, age, season and the years.