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ABS-ELISA检测46例结直肠癌患者血清可溶性CD137L浓度 被引量：1

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摘要 目的建立一种灵敏、可靠的检测血清可溶性CD137L(sCD137L)浓度的方法。方法建立链霉亲和素-生物素-ELISA检测27例结肠癌患者、19例直肠癌患者以及15例健康对照者血清sCD137L水平。结果46例结直肠癌患者血清sCD137L的平均浓度为(1091.48±519.32)pg/ml,显著高于健康对照组[(4.36±2.94)pg/ml](P<0.01)。结论结直肠癌患者血清sCD137L水平显著升高,血清sCD137L浓度在结直肠癌的诊断及疗效评估、预后判断中可能具有一定的临床价值。
作者 杨琳 黄娜 苏宁 李爱民 吕成伟 廖旺军 罗荣城
机构地区 南方医科大学南方医院肿瘤中心 解放军广州疗养院一科
出处 《南方医科大学学报》 CAS CSCD 北大核心 2009年第2期337-338,共2页 Journal of Southern Medical University
基金 广东省自然科学基金(7005208)
关键词 CD137L ELISA 结直肠癌 血清 亲和素 生物素
分类号 R735.3 [医药卫生—肿瘤]
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参考文献10

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二级参考文献22

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共引文献8

同被引文献6

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南方医科大学学报
2009年 第2期

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