老年与青中年多器官功能衰竭的对照研究

The comparative research on multiple organ failure in the elderly and middle-aged patients

目的探讨老年人多器官功能衰竭的主要病因、临床特点及影响预后的因素。方法选择96例多器官功能衰竭患者,按年龄分为老年组(≥65岁,50例)与青中年组(15～60岁,46例),对两组的临床资料进行对比分析。结果老年组与青中年组相比,在严重感染为诱因的病例数及器官功能衰竭的数目及病死率等方面存在显著性差异。结论老年人多器官功能衰竭的主要病因为严重感染,尤以肺感染为最多,衰竭脏器数和基础疾病数是影响预后的重要因素。

Objective To study the clinical features,etiology and prognosis of multiple organ failure in the elderly（MOFE）. Methods Ninety-six cases of multiple organ failure were enrolled and divided into 2 groups according to age： old group（≥65 years old,50 cases） ,young group （15-60 years old,46 cases）. Clinical data of the two groups were compared and analysed. Results Comparison between the old group and young group showed that the number of cases with serious infections as the predisposing cause, the number of organs with function failure and the fatality rate were obviously different. Conclusion The major etiology of MOFE is serious infections, especially the lung in-fection. The number of organs in failure and basic diseases are the important factors influencing prognosis.