养血清脑颗粒对颅脑损伤后记忆障碍的影响

The Efficacy of Yangxue Qingnao Granule in Treatment of Brain Injury Induced Memory Decreasing

目的:评价养血清脑颗粒对颅脑损伤后记忆减退的治疗作用。方法:选择颅脑损伤后记忆减退患者130例,随机分为养血清脑颗粒治疗组和常规治疗加淀粉对照组,每组各65例,两组在常规治疗的基础上分别服养血清脑颗粒和淀粉每次4.0g,3次·d-1,共4周,于治疗前和治疗4周后进行记忆商的测定,同时进行不良反应的观察。结果:按临床疗效标准,养血清脑颗粒组总有效率87.7%,对照组为40.3%,两组经统计学分析示有显著差异(P<0.01)。患者的记忆力提高,养血清脑颗粒组平均增值17±11分,对照组平均增值5±7分,两组间比较P<0.01。养血清脑颗粒的不良反应较小。结论:养血清脑颗粒对颅脑损伤后的记忆减退有较好的恢复作用。

Objective：To evaluate the efficacy of yangxue qingnao granule in the treatment of brain injury induced memory decreasing. Methods：The total of 130 patients with brain injury induced memory decreasing were randomly divided to group one （receive yangxue qingnao granule in a regimen of 4.0 g tid for 4 weeks） and group two amylum in a regimen of 4. 0 g tid for 4 weeks）. Both groups were evaluated the anamnesis before and 4 weeks after reatment, meanwhile, side effects were observed. Results： The total response rate was 87.7% for yangxue qingnao granule group and 40.3% for amylum group,there was significant difference between the two groups. The mean memory quotient increase was 17 ± 9 for yangxue qingnao group and 5 ± 7 for amylum group and there was significant difference between the two groups. Conclusion： Yangxue qingnao granule had an good effect on restoring memory decreasing induced by brain injury. Yangxue qingnao granule had less side effects.