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过氧化物酶体增殖因子活化受体γ在垂体腺瘤中的表达及其意义 被引量：1

Expression and It's Significance of Peroxisome Proliferator-Activated Receptor γ in Pituitary Adenomas
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摘要 目的:观察过氧化物酶体增殖因子活化受体γ(PPARγ)在垂体腺瘤组织中的表达情况,分析PPARγ与垂体腺瘤激素免疫分型等之间的关系。方法:选取2002年1月—2005年5月38例手术切除的垂体腺瘤,利用RT-PCR和Western Blot技术分析PPARγ在垂体腺瘤中的表达情况及其与垂体腺瘤激素免疫分型等之间的关系。结果:所有肿瘤均发现有PPARγ的表达。按照垂体腺瘤激素免疫分型各组肿瘤表达的PPARγ mRNA和PPARγ蛋白表达水平均无显著差异。结论:人类垂体腺瘤中有PPARγ的表达。 Objective：To study the expression of PPARγ in pituitary adenomas and analysis the role of PPARγ in hormone typing of pituitary adenomas. Methods：The 38 consecutive pituitary adenoma patients between Jan 2002 to May 2005 were enrolled in this study. Their specimens were analyzed by RT-PCR and Western blot technique. Results： PPARγ was found expressed in pituitary adenomas. According to the hormone typing, there was no significant different expression of PPARγ in every groups. Conclusion： Human pituitary adenomas could expressed PPARγ.
作者 陈开来 鲁晓杰 季卫阳 王清 李兵 孙继勇 李江安
机构地区 南京医科大学附属无锡第二人民医院神经外科
出处 《中国临床医学》 2009年第1期44-46,共3页 Chinese Journal of Clinical Medicine
关键词 过氧化物酶体增殖因子活化受体Γ 垂体腺瘤 Peroxisome proliferator-activated receptors γ Pituitary adenomas
分类号 R743 [医药卫生—神经病学与精神病学]
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参考文献5

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同被引文献8

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引证文献1

中国临床医学
2009年 第1期

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