新型隐球菌脑膜脑炎的影像学研究

Radiological Study on Cryptococcus Meningoencephalitis

目的:探讨新型隐球菌脑膜脑炎的CT、磁共振成像(MRI)表现及其在艾滋病患者的影像特点。方法:回顾分析经病原学证实的16例新型隐球菌脑膜脑炎患者(其中9例为艾滋病患者,7例非艾滋病患者)头颅CT及MRI的表现,比较CT、MRI对其影像征象的显示能力和其在艾滋病患者的影像特点。结果:新型隐球菌脑膜脑炎的主要影像学表现为脑实质内的胶状假囊、脑膜强化、脑积水及脑萎缩。MRI在检测影像征象上明显优于CT,其在艾滋病患者的影像表现明显轻于非艾滋病患者。结论:MRI对新型隐球菌脑膜脑炎病灶的检出明显优于CT,能有效显示该病的影像特征,辅助临床诊断并可观测疗效。

Objective：To study the main neuroradiological manifestation of cryptococcus meningoencephalitis （CM） and the radiological features of acquired immune deficiency syndrome （AIDS） patients. Methods： The findings of computed tomograghy （CT） and magnetic resonance imaging （MRI） were retrospectively analyzed in 16 cases proved by finding cryptococcus neoformans in cerebrospinal fluid,9 cases were AIDS patients, while 7 cases were non-AIDS patients. Results： The main radiological features were gelatinous pseudocysts, meningeal enhancement, brain atrophy and hydrocephalus. Conclusion： MRI has higher sensitivity of lesion detection compared with CT, can provide useful information about CM and monitoring the response to therapy.