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2007年广州市流行性感冒病原学及血清学监测分析 被引量:6

The Virological and Serological Surveillance of Influenza in Guangzhou in 2007
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摘要 目的分析2007年广州市流行性感冒的流行特征。方法监测来自广州市3家监测医院的流感样病例的漱口液或咽拭子标本,采用MDCK细胞进行病毒分离,通过红细胞凝集实验和红细胞凝集抑制实验进行鉴定;按0~、5~、15~、25~、60~以上5个年龄组分层随机抽取健康人群的血清标本,采用红细胞凝集抑制实验检测血清中的各型流感抗体。结果全年共对1068份流感样病例标本进行了病毒分离,共分离出46株流感病毒,分离率为4.3%,其中H3N2型15株(32.6%),B(Yamagata)型27株(58.7%),B(Victoria)型4株(8.7%),未分离出H1N1型流感病毒株。60~组人群的病毒分离率最高,为7.7%;健康人群血清中流感抗体的阳性率不高,最高为10月份H3N2的抗体阳性率,为44%,最低为3月份B(Yamagata)的抗体阳性率,仅为6.7%。结论2007年广州市流感病毒的流行时间有明显的季节性,流感病毒的活动相对平缓,B(Yamagata)型流感病毒是2007年的优势株,主要是在夏季和25~岁组的人群中流行。流感对老年人的威胁最大,有必要针对老年人加强流感的预防工作。 Objective To analysis the characteristics of influenza in Guangzhou in year 2007. Method The pharynx wash or swab specimens were collected from influenza-like patients in three sentinel hospitals, and were isolated by MDCK cells and examined by hemagglutination (HA) test and hemagglutination inhibition (HI) test; serum specimens were collected randomly in five different age groups: 0, 5, 15, 25, and 60, and were examined by hemagglutination inhibition (HI) test. Result 1068 specimens from influenza-like patients were isolated by MDCK cells. 46 of those were identified as influenza virus, with the positive rate of 4.3%. Among those specimens, 15 (32.6%) were identified as H3N2, 27(58.7%) were B(Yamegata), 4(8.7%) were B(Victoria), and none of H1N1 was isolated. The highest positive rate (7.7%) was found in the group aged 60. The positive rate of influenza antibody in serum was low, with the highest of H3N2 antibody in serum collected in October (44%), the lowest of B (Yamegata) antibody in serum collected in March(6.7%). Conclusion The epidemic of influenza virus is seasonal and not so active. B(Yamegata) was the predominate subtype in 2007, it was epidemic in summer and the group aged 25. Influenza is a big threaten for the elders, and it is necessary to strengthen the prevention of influenza among the elders.
出处 《热带医学杂志》 CAS 2009年第2期199-201,210,共4页 Journal of Tropical Medicine
基金 广州市科技计划项目(No.2006J1-C0141) 广州市医学科学技术研究重点项目(No.2006-ZDi-10)
关键词 流行性感冒 病原学监测:抗体检测 influenza surveillance antibody test
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  • 1徐红.2002~2003年中国南、北方地区流感监测分析[J].世界感染杂志,2003,3(4):282-285. 被引量:13
  • 2郭元吉,郭忠明,张莎林,沈桂章,刘凌雁,许凤琴,董振英,王美华,孙小林,诸葛亚辉,黄雅,吴淑敏.我国流感监测(1990~1993)[J].中华实验和临床病毒学杂志,1994,8(1):11-15. 被引量:42
  • 3倪汉忠,鄢心革,张欣,柯昌文,彭国文,周慧琼.2000—2003年广东省流感监测结果分析[J].海峡预防医学杂志,2005,11(4):4-6. 被引量:11
  • 4倪汉忠,鄢心革,张欣,郑夔,柯昌文,周惠琼.广东省1991—2004年乙型流感监测结果分析[J].海峡预防医学杂志,2006,12(3):12-14. 被引量:6
  • 5Williams JR,Chen PY,Cho CT,et al.Influenza:prospect for prevention and control[J].Kachsing J Med Sci,2002,18(9):421 ~ 434.
  • 6Klaus Stohr.The global agends on influenza surveillance and control[J].Vaccine,2003,21:1744 ~ 1748.
  • 7BERTON MT,NAEVE CW.Antigenic structure of the influenza B virus hemagglutinin nucleotide sequence analysis of antigenic variants selected with monoclonal antibodies[J].Virol,1984,52(3):919-927.
  • 8SAIKI RK,GELFAND DH,STOTTELS A,et al.Primerdirected enzymatic amplification of DNA with a thermostable DNA polymerase[J].Science,1988,239:487-491.
  • 9WILSON IA,COX NJ.Structural basis of immune recognition of influenza virus hemagglutinin[J].Annu Rev Immunol,1990,8:737-771.
  • 10ISABELLE H,YAN L,MICHAEL B,et al.Molecular evlution of influenza AP H3N2 viruses in the provinces of Quebec(Canada)during the 1997-2000 period[J].Virus Research,2001,77:89-96.

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  • 1黄建云,林文生,佘焕昭,姚丽君,张旭彬,廖朝晖.汕头市2002~2004年流感监测结果分析[J].热带医学杂志,2005,5(5):666-667. 被引量:6
  • 2李立明.流行病学[M].北京:人民卫生出版社,2007.454.
  • 3广东省卫生厅办公室.广东省霍乱等部分传染病及病媒生物监测方案(试行)[EB/OL].[2005-08-02].http://www.edcp.org.cn/viewArticle.do?method=viewArticle&id=2c9087840f5fb152010f6t3f62d90021.
  • 4Interim planning considerations for mass gatherings in the context of pandemic (H1N1) 2009 influenza, http: //www. who. int/esr/resources/publications/swineflu/h1n1_mass gatherings/en/index. html.
  • 5Pandemic influenza preparedness and response, http: //www. who. int/esr/disease/influenza/pipguidance2009/en/index. html.
  • 6广东省卫生厅网站.深圳市报告1例甲型H1N1流感死亡病例[Z].2011年2月11日.
  • 7陈继军,李志远,李莹,张莉.兰州市吸毒人群艾滋病流行病学调查分析[J].现代预防医学,2007,34(17):3299-3300. 被引量:6
  • 8张文彤.SPSS11统计分析教程(高级篇)[M].北京:北京希望电子出版社,2002.300-310.
  • 9黄飞;林鹏;李艳.艾滋病预防控制工作指南[Z],2009.
  • 10Novel Swine-Origin Influenza A (H1N1) Virus Investigation Team,Dawood FS,Jain S. Emergence of a novel swine-origin influenza A (H1N1) virus in humans[J].New England Journal of Medicine,2009,(25):26052615.

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