肺结核分枝杆菌在不同标本类型中的分布

The Distribution of Mycobacterium Tuberculosis in Different Types of Samples.

目的讨论不同标本类型对肺结核分枝杆菌的检出率有何差异。方法对52例临床诊断肺结核患者的痰液、支气管灌洗液、血液进行荧光定量PCR检测。结果52位患者经荧光定量PCR检测痰液中检出45例(86.54%),支气管灌洗液中检出51例(98.08%),血液中检出15例(28.85%),经统计学统计痰液与支气管灌洗液之间χ2=4.875,P<0.05具有统计学意义,血液与痰液之间χ2=17.23,P<0.05具有统计学意义。结论肺结核分枝杆菌在支气管灌洗液中检出率最高,其次为痰液,检出率最低为血液。

Objective To study the difference in detection rate of Mycobacterium tuberculosis in diffenent types of sumples. Methods The sputum, bronchial fluid, blood of 52 patients with clinical diagnosis of patients with pulmonary tuberculosis were tested with fluorescence quantitative PCR. Results 45 cases were identiified in sputum and 51 cases were identified in bronehial perfusate and 15case were identified in blood.χ^2 was 4. 875 （P 〈 0.05） in terms of detection rate between the group of sputum liguid and the group of bronchial perfusate. The difference was significant. The χ^2 was 17.23 （ P 〈 0.05 ） in terms of detection rate between the group of blood and the group of sputum. The difference was significant too. Conclusion The detection rate is highest in the bronchial fluid of myeo baeterium tubereulosis followed by sputum, and the detection rate is the lowest in blood sample.