摘要
应用快速有效的数学统计方法对Pseudomonassp.H18的脂肪酸发酵条件进行了优化。采用Plackett-Burman设计对影响产酶的重要因素进行了筛选,然后利用响应面分析(RSA)法对这些产酶重要影响因素进行了优化,各因素的最佳水平通过Box的complexalgorithm法得以确定。
Statistical methods and optimization techniques were used to determine the optimumfermentation conditions for lipase production by Pseudomonas sp. H18 in shake flask cultivation.A Plackett-Burman design was used to screen the important variables, which were thencegrouped and stUdied by the Response Surface Analysis (RSA) method. The optimum levels ofthese variables were established by the complex algoritrhm of Box.
出处
《微生物学通报》
CAS
CSCD
北大核心
1998年第2期94-97,共4页
Microbiology China
关键词
优化
脂肪酶
假单胞菌
发酵条件
Statistical methods, Optimization. Plackett-Burman design, Lipase, Pseudomonas sp