人工操纵病毒的原子力显微镜研究

Atomic Force Microscopy Study of the Manipulation of Virus.

人工操纵生物大分子是目前科学研究的一个前沿领域，我们利用改进的“分子梳”方法，首次实现了复杂的体系———一种线性噬菌体病毒的人工拉直与定向．这种操纵是在大面积平整的固体表面实现的，并利用原子力显微镜对拉直前后的病毒进行了观察与测量．

Manipulation of macromolecules is becoming an interesting research subject both in physics and biology recently. Linear phage virus has been aligned in one direction on atomic flat surfaces by a special method named “molecular combing”. Atomic force microscopy was used to check the results. The related mechanism has been discussed.