5Furchgott RF,Zawadzki JV.The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine[J].Nature,1980,288(5789):373-376.
6Perticone F,Ceravolo R,Pujia A,et al.Prognostic significance of endothelial dysfunction in hypertensive patients[J].Circulation,2001,104(2):191-196.
7Johnson FK,Johnson RA,Peyton KJ,et al.Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension[J].Am J Physiol Regul Integr Comp Physiol,2005,288 (4):R1057-1062.
8Klingbeil AU,John S,Schneider MP,et al.Effect of AT1 receptorblockade on endothelial function in essential hypertension[J].Am J Hypertens,2003,16(2):123-128.
9Nitenberg A,Chemla D,Antony I.Epicardial coronary artery constriction to cold pressor test is predictive of cardiovascular events in hypertensive patients with angiographically normal coronary arteries and without other major coronary risk factor[J].Atherosclerosis,2004,173 (1):115-123.
10Xenos ES,Stevens SL,Freeman MB,et al.Nitric oxide mediates the effect of fluvastatin on intercellular adhesion molecule-1 and platelet endothelial cell adhesion molecule-1 expression on human endothelial cells[J].Ann Vasc Surg,2005,19(3):386-392.
1Welch GN,Loscalzo JN.Homocysteine and atherothrombosis[J].N Engl J Med,1998,338(15):1042-1045.
2Boushey CJ,Beresford SAA,Omenm BS,et al.A quantitative assessmentofplasma homcysteine as a risk factor forvasculardisease[J].JAMA,1995,274:1049-1057.
3GuoH,Lee JD,Xing Y,et al.Changes of homocysteine levels and arterial endothelia function in patientswith high risk of coronary artery disease after 6-month folic acid supplementation[J].Acta Cardio,l 2004,59(5):503-506.
4Kaare Harald Bonaa,M.D.Ph.D.Inger Njolstad,M.D.Ph.D.Per Magne Ueland,M.D,Ph.D.Henrik Schirmer,M.D.Ph.D.Aage Tverdal,Ph.D,Terje Steigen,M.D.Ph.D.Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction[J].The new england journal of medicine,2006,354:1578-1588.
6Boushey CJ, Beresford SAA, Omenm BS, et al. A quantitative assessmentofplasma homcysteine as a risk factor forvasculardisease [J]. JAMA, 1995, 274 : 1049 - 1057.
7Guo H, Lee JD, Xing Y, et al. Changes of homocysteine levels and arterial endothelia function in patientswith high risk of coronary artery disease after6- month folic acid supplementation[ J ]. Acta Cardio, 2004, 59(5) : 503 - 506.
8Kaare Harald Bonaa, Inger Njolstsd, Per Magne Ueland, et al. Homocysteine Lowering and Cardiova- scular Events after Acute Myocardial Infarction[J]. The new england journal of medicine, 2006, 354 : 1578 - 1588.
9陆再英,钟南山.内科学[M].7版北京:人民卫生出版社.2008:394.
10Goldstein LB,Bushnell CD,A dams RJ,et al.Guidelines for the primary prevention of stroke:a guideline for healthcare prefessionals from the American Heart Association/American Stroke Association.Stroke,2011,42(2):517-584.