亲属脾移植术后移植物抗宿主反应和移植脾亢的成功治疗经验

Successful treatment of graft versus host reaction and graft hypersplenism after relative spleen transplantation

移植物抗宿主反应（ＧＶＨＲ）和移植脾亢是脾移植的两个棘手问题。因二者来势凶猛，控制困难，既往治疗常是切除移植脾脏。我们介绍一例父亲供脾移植术后７天和２１天发生ＧＶＨＲ和移植脾亢。

There are two knotty problems in spleen transplantation, graft versus host reaction (GVHR) and graft hypersplenism, which are very dangerous and uncontrolled. The previous treatment was to remove the spleen graft. Presented in this paper was one case of relative (father to son) spleen transplantation for treating hemophilia A. GVHR and hypersplenism occurred on 7th day and 21st day after transplantation. Satisfactory therapeutic effect was obtained through the region irradiate with deep Xray and Co60 respectively.